Huahana Huahana

Huahana Huahana

ʻO Quickmice™ Fast CKO Mouse Hoʻopilikino

ʻO Conditional Knock-out (CKO) kahi ʻenehana hoʻopaʻa kino kikoʻī kikoʻī i loaʻa e kahi ʻōnaehana hoʻohui kūloko.

ʻO kekahi o nā pōmaikaʻi nui o ka conditional knock out, ʻo ia ka hiki ke aʻo i ka hana gene ma kahi ʻano hoʻomalu.Ma ke koho ʻole ʻana i nā genes i nā manawa kikoʻī a i ʻole nā ​​kiko kikoʻī, hiki i nā mea noiʻi ke nānā i nā hopena o ka nalo ʻana o ka gene a loaʻa nā ʻike i nā ʻano kumu o nā kaʻina hana olaola.

Ma kahi o 10-12 mau mahina e hana ai i ka ʻiole CKO me ka helu kūleʻa haʻahaʻa me ka hoʻohana ʻana i ka ʻōnaehana Cre/LoxP kuʻuna, no ka mea, pono kēia ʻōnaehana i nā ʻiole Flox e hoʻopā me ka ʻiole me ka ʻōlelo kikoʻī o Cre.

He hanauna hou o ka ʻenehana Hoʻomākaukau ʻIole Rapid

TurboMice™

Hiki iā mākou ke hāʻawi koke iā ʻoe i nā hiʻohiʻona ʻiole homozygous CKO ma o ka hoʻohana ʻana i ka ʻenehana TurboMice™ e hoʻomaikaʻi i ka helu kūleʻa.

Ma muli o ka papahana hoʻoponopono gene maikaʻi loa e kā mākou ʻepekema, hiki iā mākou ke hoʻopau i ka nānā ʻana i nā pūnaewele embryonic i hoʻoponopono ʻia i loko o 3-5 mau lā, a laila kūkulu i ka embryo tetraploid.Ma hope o ka maternal surrogacy, hiki ke loaʻa nā ʻiole homozygous humanized i loko o 2-4 mau mahina, hiki ke mālama i nā mahina 7-8 no nā mea kūʻai.

Mea lawelawe

Hana No. Nā kuhikuhi kikoʻī Maikaʻi hoʻouna pōʻaiapuni hoʻouna
MC003-1 lōʻihi o ka gene hoʻokahi <5kb 3-9 mau ʻiole kāne homozygous CKO 2-4 mahina
MC003-2 lōʻihi o ka gene hoʻokahi <5kb 10-19 mau ʻiole kāne homozygous CKO 2-4 mahina
MC003-3 lōʻihi o ka gene hoʻokahi <5kb 20 CKO nā ʻiole kāne homozygous 3-5 mahina
MC003-4 ʻO ka lōʻihi o ka gene hoʻokahi he 5kb-10kb 3-9 mau ʻiole kāne homozygous CKO 3-4 mahina
MC003-5 ʻO ka lōʻihi o ka gene hoʻokahi he 5kb-10kb 10-19 mau ʻiole kāne homozygous CKO 3-4 mahina
MC003-6 ʻO ka lōʻihi o ka gene hoʻokahi he 5kb-10kb 20 CKO nā ʻiole kāne homozygous 3-5 mahina

Kāhea iā mā˚ou

E ʻoluʻolu e launa pū me mākou ma:

1) E ʻoluʻolu e hoʻoiho a hoʻopiha i ka palapala ma lalo nei《Palapala Noi Noi》, a hoʻouna ma ka leka uila iāMingCelerOversea@mingceler.com;

2) Tel: +86 181 3873 9432;

3) LinkedIn:https://www.linkedin.com/company/mingceler/

Palapala Noi Noi.docx

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