Huahana Huahana

Huahana Huahana

ʻO Quickmice™ Fast KI Mouse Hoʻoponopono

quickmice-fast-ki-mouse-customization-huahana

ʻO Knock-in (Knock-in, KI) kahi hana e hoʻohana ai i ka homologous recombination o nā genes e hoʻololi i kahi gene functional exogenous i loko o kahi kaʻina homologous i loko o ke kelepona a me ka genome, a loaʻa ka hōʻike maikaʻi i loko o ke kelepona ma hope o ka hui hou ʻana.

He 5-6 mau mahina e kiʻi ai i nā ʻiole heterozygous Neo-deleted a me ka huina o 10-12 mau mahina e kūkulu i kahi kiʻi kiʻi kiʻi homozygous KI me nā helu kūleʻa haʻahaʻa me ka hoʻohana ʻana i nā ʻenehana kuʻuna, no ka mea, he haʻahaʻa ka chimera positivity o kēia mau ʻano a koi aku i ka male ʻana me ka ʻiole. e kiʻi i nā ʻiole heterozygous Neo-deleted, a laila hoʻohua i nā ʻiole heterozygous hānau no 2-3 mau hanauna e loaʻa ai nā ʻiole KI homozygous.

He hanauna hou o ka ʻenehana Hoʻomākaukau ʻIole Rapid

TurboMice™

Hiki iā mākou ke hāʻawi koke iā ʻoe i nā kiʻi kiʻi kiʻi homozygous KI ma o ka hoʻohana ʻana i ka ʻenehana TurboMice™ e hoʻomaikaʻi i ka helu kūleʻa.

Ma muli o ka papahana hoʻoponopono gene maikaʻi loa e kā mākou ʻepekema, hiki iā mākou ke hoʻopau i ka nānā ʻana i nā pūnaewele embryonic i hoʻoponopono ʻia i loko o 3-5 mau lā, a laila kūkulu i ka embryo tetraploid.Ma hope o ka maternal surrogacy, hiki ke loaʻa nā ʻiole homozygous humanized i loko o 2-4 mau mahina, hiki ke mālama i nā mahina 7-8 no nā mea kūʻai.

Mea lawelawe

Hana No. Nā kuhikuhi kikoʻī Maikaʻi hoʻouna pōʻaiapuni hoʻouna
MC002-1 lōʻihi o ka gene hoʻokahi <5kb 3-9 KI nā ʻiole kāne homozygous 2-4 mahina
MC002-2 lōʻihi o ka gene hoʻokahi <5kb 10-19 KI nā ʻiole kāne homozygous 2-4 mahina
MC002-3 lōʻihi o ka gene hoʻokahi <5kb 20 KI nā ʻiole kāne homozygous 3-5 mahina
MC002-4 ʻO ka lōʻihi o ka gene hoʻokahi he 5kb-10kb 3-9 KI nā ʻiole kāne homozygous 3-4 mahina
MC002-5 ʻO ka lōʻihi o ka gene hoʻokahi he 5kb-10kb 10-19 KI nā ʻiole kāne homozygous 3-4 mahina
MC002-6 ʻO ka lōʻihi o ka gene hoʻokahi he 5kb-10kb 20 KI nā ʻiole kāne homozygous 3-5 mahina

Kāhea iā mā˚ou

E ʻoluʻolu e launa pū me mākou ma:

1) E ʻoluʻolu e hoʻoiho a hoʻopiha i ka palapala ma lalo nei《Palapala Noi Noi》, a hoʻouna ma ka leka uila iāMingCelerOversea@mingceler.com;

2) Te: +86 181 3873 9432;

3) LinkedIn: https://www.linkedin.com/company/mingceler/

Palapala Noi Noi.docx

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